Multiple Sclerosis (MS), also known as disseminated sclerosis, is a chronic disease of the central nervous system. It causes damage to the brain, spinal cord, optic nerves, and other parts of the body. Out of all neurological diseases, MS is one of the most prevalent, affecting more than 2.3 million people worldwide. It's also considered as one of the most debilitating of autoimmune diseases. If left untreated, the progressive form leads to neurological disability and various kinds of irreversible disability.
Patients with MS are facing 3 main physiological challenges:
The goal of stem cell treatments for MS is to regulate the immune system, reduce the damage done to the nerve cells, and repair injured tissue.
Stemaid programs are 2-5 weeks in length, depending on your condition and severity of your symptoms. Every candidate for stem cell therapy receives a customized plan to help achieve the highest success rate, however, a "typical" plan for the treatment of patients with this condition might include the following over 5 weeks plus weekly visits for 6 months.
25 stem cell IVs, plus additional weekly IVs for 6 months
5 Plurisomes IVs, plus additional weekly IVs for 6 months
regular CaNa2 EDTA IVs
Efficacy of stem cell therapy depends on types of cells. There are numerous types of stem cells available for treatment of this neurological disorder. Adult stem cells, mesenchymal stem cells, bone marrow stem cells, adipose-derived mesenchymal stem cells, and neural stem cells are used at clinics around the world. At Stemaid Institute, we utilize the most comprehensive and potent pluripotent stem cells. This cell-based therapy is unique in that it signals repair in all parts of the body at once and repairs injured tissue in the central and peripheral nervous system.
Pluripotent stem cells can repair the nerve tissue in the brain and in the periphery, balance the immune system and help recover the lost physical and organ function. With each injection, self-healing mechanisms are triggered and disease activity gradually attenuated.
First-Line therapies and conventional therapies for MS generally do not include cellular therapies at this time. This is however changing. Clinical application of different type of stem cells for neurological disorders and autoimmune disorders is gaining more popularity for a good reason. Mesenchymal stem cell therapy in treatment of injured tissue is available in some jurisdictions.
hESC treatment with pluripotent factors, like the one being utilized at Stemaid Institute, is now recognized as the most potent whole body repair and rejuvenation treatment strategy. The effects are seen gradually, with highest protective effects between 12 to 180 days post treatment. This is a long term treatment. The epigenetic reprogramming that occurs with pluripotent cellular therapies is the next frontier in biological medicine for neurological disorders and autoimmune disorders.
Pluripotent hESC treatment can be administered by intravenous, intra-muscular and lumbar puncture routes.
In addition to our Standard line, Autologous transplantation of pluripotent stem cells is also possible with Stemaid Laboratories Autologous Pluripotent Stem Cell line. Get in touch to learn more about the different types of cells available at Stemaid Institute.
One of the key beneficial effects of stem cell treatment is immune regulation. The immunomodulatory effects of hESC treatment are critical in easing the inflammatory phase of MS. Pluripotent stem cells and exosomes release transcription factors that help immune cells to shift away from TH1 autoimmune reactivity. Detoxification IVs and anti-parasite treatments also help with this inflammatory disease. This calms the fire destroying the axonal integrity and allows the myelin sheath to restore.
The second level of therapeutic effects is usually observed after a minimum of 1-2 weeks, when inflammatory fire is quenched and the myelin sheath and other injured tissue have a chance to start restoring. Growth factor peptides, nerve growth factor peptides, mRNAs & miRNAs signal renewal, repair, and regeneration in the brain and in the periphery. The parenthesis, numbness, tingling, burning, all gradually start to improve.
After about 4-5 weeks of clinical application, neuromuscular junctions and larger muscle groups begin to show signs of repair and recovery. The progressive phase of MS, the key degenerative component, shows signs of slowing down. Speaking, swallowing, movement and strength begin to gradually return. Dizziness wanes and balance improves. The results depend on the severity of the MS and which part of the brain and/or spinal cord is originally impacted. Healing takes time. Our clinical studies with MS show a dramatic decrease in disability status scale over time. Get in touch for more information on our treatment of patient with MS and our case study.