What Are Pluripotent Stem Cells?
Pluripotent stem cells are the mothers of all cells, including other stem cells. They are the earliest form of cells found at the early stage of life, within the first few days after conception.
It is from these cells that the body forms with more than 200 types of cells, all specialized from these initial pluripotent stem cells.
The fact that these pluripotent stem cells are not specialized means that their DNA hasn’t been limited in its expression yet. They are able to express microRNA, peptides and proteins that no other stem cells can express and this is why they have an unmatched capacity to heal and restore youth in all organs.
Pluripotent stem cells are the only type of stem cells that we chose to offer at Stemaid Institute.
Where Do Pluripotent Stem Cells Come From?
The initial main source of pluripotent stem cells is the early stage of an embryo ( 5 days old), called a blastocyst which contains between 100 and 200 pluripotent stem cells in its inner mass.
In this stage, the function of the cell is not yet determined. That means it is not a blood cell, or muscle cell or bone cell yet.
When these early-stage cells are cultured in a laboratory, they can multiply and grow for a long time. Stemaid scientists are still growing the initial line that was prepared 15 years ago.
There are now other ways to prepare pluripotent stem cells. One of them was developed by Pr Yamanaka who induced the state of pluripotency into skin cells by placing specific pluripotent genes in these cells. The resulting induced pluripotent stem cells, iPSC, acts in many ways as the pluripotent stem cells derived from an embryo although they have been shown to miss some key functions.
Stemaid scientists also developed protocols to create pluripotent stem cells out of a fibroblast using a multi-step technique that involves the cloning of a skin cell. The process takes 3 months in our laboratory to prepare after we receive a skin sample. The resulting autologous embryonic stem cells, AESC, behave exactly as the regular pluripotent stem cells and have, in addition, the exact genetic makeup of the recipient and can, therefore, become part of the recipient’s body, bringing its youth and clean epigenetic.
What Do Pluripotent Stem Cells Do?
Pluripotent stem cells have the ability to message all cells in your body, in order to regenerate the target area.
As opposed to adult, or mature, stem cells (which can only express miRNA and proteins for the cells from the area they came from), pluripotent stem cells actually can express the DNA of all the 220 cell types of the body plus the pluripotency genes that carry rejuvenation. As soon as they enter the bloodstream, they start working by releasing extracellular vesicles that reach all areas of the body and carry the signal to begin the process of regeneration and repair.
This signaling, which occurs within 30 minutes, causes, among other mechanisms, the release of stem cells from various parts of the body that are responsible for repair. Therefore, the brain starts to release neural stem cells, the heart releases cardiac progenitor cells, and so on. The signaling exosomes of the pluripotent stem cells not only trigger the release of the recipient’s own adult stem cells, they also contain anti-inflammatory factors, anti-fibrotic factors, senolytic factors as well as growth factors. Because of these multiple effects, pluripotent stem cells are the most potent stem cells to treat degenerative conditions.
Depending on the conditions, pluripotent stem cells can be delivered through the bloodstream or directly to the organ that is in need of repair.
After the signaling is complete, it is important to know that the pluripotent stem cells do not stay embryonic, they naturally differentiate into one of the 220 cells that they are supposed to become. Once they have differentiated into a skin cell, a heart cell or any cell, the body’s immune system naturally removes them, unless they were made from the recipient’s own fibroblasts. By using Stemaid’s standard line of pluripotent stem cells, one benefits from their powerful signaling for up to 36h while the use of one’s autologous pluripotent stem cells derived from a fibroblast, allows for the same powerful signaling but also brings additional rejuvenation and repair as the differentiated cells can stay in the body and become part of its organ.
What To Expect From Treatments
On your first day at the Stemaid Institute you will be asked to do the following:
- An initial consultation with the doctors
- Bioresonance tests, looking for imbalance and for the presence of various viruses, bacteria, mold and heavy metals in the body
- Blood tests, the nursing staff will take 2-3 vials of your blood to be fully analyzed where we find out a full range of metabolic panels
These tests are helpful in providing your full health and medical state and picture. Based on the resulting profile, we can then determine the best treatment plan for you, to ensure the best results for the time of your stay.
Treatment will start on your first day. The treatment time depends on how many intravenous injections you will receive. Daily procedures take about 3 hours.
The healing process is not linear. Most clients experience improvement towards the end of the treatment which keeps progressing for at least 3 months after the treatment is completed.
What Conditions Are Pluripotent Stem Cell Therapy Useful For?
Pluripotent stem cell therapy is being used for a number of conditions, and the list grows continually. In fact, if your condition is not on the list below, we encourage you to set-up an assessment to see if treatment does exist for your specific case.
Commonly treated conditions include:
- Anti Aging
- Alzheimer’s Disease
- Brain Injury
- Cerebral Palsy
- Heart Disease
- Lyme Disease
- Multiple Sclerosis
- Opioid Addiction
- Pulmonary Fibrosis
To learn more about stem cell therapy using pluripotent stem cells, or to see if you are a candidate, please contact us directly to set-up an appointment.